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KMID : 0363620160370030074
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Journal of Korean Oriental Medicine
2016 Volume.37 No. 3 p.74 ~ p.86
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A review of traditional Korean medical treatment for cancer-related cognitive impairment
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Lee Hye-Yoon
Kim Jung-Eun
Kim Mi-Kyung
Kim Joo-Hee
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Abstract
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Objectives: This article aims to review clinical studies related to traditional Korean medicine (TKM) for cancer-related cognitive impairment (CRCI) up to date.
Methods: EMBASE, Pubmed and eight Korean databases were searched for clinical studies about TKM for CRCI up to July 2016. We selected articles about subjects with cancer, using TKM interventions including acupuncture, moxibustion or herbal medicine, containing assessment about cognitive function.
Results: Two randomized controlled trials (RCTs) and one randomized controlled feasibility study were included. Selected studies were containing assessments about cognitive function but not as primary outcomes. The three studies included one acupuncture study and two herbal-medicine studies. Only one herbal-medicine study showed improvement in cognitive function.
Conclusions: Few clinical studies mainly focusing CRCI treated with TKM have been performed and have shown contradictory results until now. Future studies should be performed considering findings from pre-clinical and clinical studies altogether, and they should be controlled to minimize risk of bias thorough out overall courses of designing, conducting and reporting them.
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KEYWORD
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Cancer-related cognitive impairment, Chemotherapy-related cognitive impairment, traditional Korean medicine (TKM), acupuncture, herbal medicine
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